Student Name: Julien Thibault
Supervisors: Dr. Fiona McArdle, Karen Hickey
Funding: Strand 1 Institutes of Technology, Council of Directors
Research and Education Foundation, Sligo General Hospital.
The study conducted between the School of Science, IT sligo and the Microbiology Department at SGH focused on the antimicrobial activity of essential oils and their constituents on a range of pathogens; particularly antibiotic resistant clinical isolates such as: Methicillin Resistant Staphylococcus Aureus (MRSA), Vancomycin Resistant Enterococci (VRE), Extended Spectrum Beta lactamase producing Enterobacteriaceae (ESBL-E) as well as other clinically significant isolates. Their pathogenicity and their resistance to a large range of antibiotics forces constant and costly preventive measures in the healthcare environment. Essential oils have been used historically for various purposes but have recently gained a reputation for possessing antibacterial properties. Not all essential oils possess satisfactory activity however. Some of their active constituents contribute more than others to the oils’ activity. Reassuringly, many display antibacterial activity against the selected isolates, regardless of their resistance to antibiotics. essential oils or their constituents can therefore be used as natural antimicrobial alternatives in the fight against existing and emerging antibiotic resistant pathogens.